WHY DISURINORM®?
DISURINORM®: Relieves symptoms caused by benign prostatic enlargement (BPH). It is a reliable phytocomplex formulated with proven ingredients that support the medical treatment to be applied to stop the progression of BPH.
EFFECTIVE: Provides holistic treatment support.
SAFE: Improves the patient’s quality of life.
EASY TO USE: Easy to absorb and the effect starts fast
LIFE WITHOUT PROBLEMS: It takes control of the symptoms (signs/complaints).
DISURINORM®: Relieves symptoms caused by benign prostatic enlargement (BPH). It is a reliable phytocomplex formulated with proven ingredients that support the medical treatment to be applied to stop the progression of BPH.
EFFECTIVE: Provides holistic treatment support.
SAFE: Improves the patient’s quality of life.
EASY TO USE: Easy to absorb and the effect starts fast
LIFE WITHOUT PROBLEMS: It takes control of the symptoms (signs/complaints).
Disurinorm® EFFECTIVE
Provides a holistic treatment support
Disurinorm® IS SAFE
Improves the patient's quality of life.
Disurinorm® IS EASILY USED
It is easily absorbed, and the effect begins quickly
Disurinorm® OFFERS TROUBLE-FREE LIVING
It takes control of the symptoms (signs, complaints)
MECHANISM OF ACTION
Relaxation
Effect 6,8
Decrease in trans-capillary filtration, Venotonic, venoprotective effect
Antiinflammatory Effect 8
Decrease in the profile of proinflammatory cytokines IL-6 and IL-17
With 5 ARI 1,2,3,7,8 Effect
Antiandrogenic effect Antiproliferative effect
Antioxidant
Effect
4
Against lipid peroxidation inhibitory activity
1-Hartmann RW, Mark M, Soldati F. Inhibition of 5 α-reductase and aromatase by PHL-00801 (Prostatonin®), a combination of PY102 (Pygeum africanum) and UR102 (Urtica dioica) extracts. Phytomedicine. 1996 Sep;3(2):121-8. doi: 10.1016/S0944-7113(96)80025-0. PMID: 23194959.
2- Andersson KE, Wein AJ. Pharmacology of the lower urinary tract: basis for current and future treatments of urinary incontinence. Pharmacol Rev. 2004 Dec;56(4):581-631. doi: 10.1124/pr.56.4.4. PMID: 15602011.
3- Vahlensieck W, Theurer C, Pfitzer E, Patz B, Banik N, Engelmann U. Effects of pumpkin seed in men with lower urinary tract symptoms due to benign prostatic hyperplasia in the one-year, randomized, placebo-controlled GRANU study. Urol Int. 2015;94(3):286-95. doi: 10.1159/000362903. Epub 2014 Sep 5. PMID: 25196580.
4- Marianna N. Xanthopoulou, Tzortzis Nomikos *, Elizabeth Fragopoulou, Smaragdi Antonopoulou; Antioxidant and lipoxygenase inhibitory activities of pumpkin seed extracts; Department of Science of Nutrition-Dietetics, Harokopio University, 70 El. Venizelou Street, Athens 17671, Greece. doi:10.1016/j.foodres.2009.02.003
5- Strobl, Matthias (2004): Delta-7-Sterole und Delta-7-Sterolglykoside aus Samen von Cucurbita pepo L.: Isolierung und Strukturaufklärung. Dissertation, LMU München: Faculty of Chemistry and Pharmacy
6- European Medicines Agency Evaluation of Medicines for Human Use https://www.ema.europa.eu/en/documents/herbal-report/superseded-assessment-report-aesculus-hippocastanum-l-semen-first-version_en.pdf
7- Mayumi SUZUKI1 , Yoshihiko ITO1 , Tomomi FUJINO1 , Masayuki ABE1 , Keizo UMEGAKI2 , Satomi ONOUE1 , Hiroshi NOGUCHI1 , Shizuo YAMADA1,; Pharmacological effects of saw palmetto extract in the lower urinary tract; Acta Pharmacologica Sinica, 30(3),271-281. Doi:10.1038/aps.2009.1
8- Ooi SL, Pak SC. Serenoa repens for Lower Urinary Tract Symptoms/Benign Prostatic Hyperplasia: Current Evidence and Its Clinical Implications in Naturopathic Medicine. J Altern Complement Med. 2017 Aug;23(8):599-606. doi: 10.1089/acm.2016.0302. Epub 2017 Apr 24. PMID: 28436684.
